Rely on our long-year experience in modifying DNA oligos
Our modification centre is built on 20 years of experience.
A wide range of common and alternative modifications in different synthesis scales and purification options are available for your individual applications:
- Fluorescent dyes
Common ABI dyes such as FAM, HEX, TET, JOE, ROX
Cyanine dyes and Yakima Yellow
ATTO and Dyomics dyes
Dyes from Molecular Probes like Alexa Fluor and Bodipy dyes
- Non fluorescent modifications
Biotin and Biotin-TEG
Various Amino-modifiers
Phosphate, Thiol-modifiers
- Spacer, linker, base & sugar modifications
C3 and C18 Spacer, dSpacer (Deoxyabasic)
Modified bases such as 2'-Deoxyinosine - and uridine
Internal linkers like Amino C6-dT
- Dark quencher
Black Hole Quencher
Tide Quencher
BlackBerry Quencher 650 (BBQ650)
Dabcyl and Eclipse quencher
12MD
What you can expect from our modified DNA oligos
Product specifications:
- Synthesis scales from 0.01 to 1.0 µmol
- Purification options: HPSF, HPLC
- Sequence lengths: 5-80 bases; 5-50 bases for some 3' modifications
- Turnaround times:
- Fluorescent dyes: 3-5 working days
- Non-fluorescent modifications: 2-4 working days
- Spacers, base & sugar modifications: 2-4 working days
All relevant documents are provided in your online account:
- Oligo synthesis report
- Delivery note
- Quality report incl. QC spectra, if requested
Additional online features free of charge:
- Selectable label layouts for your oligo tubes
- Complementary sequence calculator with direct ordering
- Online status tracking
- Personal order history
Customer feedback about modified oligos
Share your opinion with us by using our feedback sheet.
"We made very positive experience with the TINA primers. We use them for routine genotyping of our genetically modified mice. Since we use TINA primers we have no more problems with one particular PCR reaction which gave us always very faint and not specific bands. With TINA primers the product of the PCR reaction is very specific and the reaction itself is much more robust. The band is easily detectable on the agarose gel. Usage of TINA primers made our routine more reliable and faster!"
Dr. Ilja Vietor, Medical University, Division of Cell Biology, Innsbruck, Austria
"Using a demographic and population genetics approach enables a better understanding of the diversity of life history traits of algae and the implications for the evolution of algal species. This is one of the main themes of the BEDIM team at the Station Biologique de Roscoff. Microsatellite markers with IRDye modified oligonucleotides for automated DNA genotyping on LI-COR systems have been used until recently. We have replaced the IRDye by DY-682 and DY-782 labeled primers without modification of our protocols and the results are always good qualities!"
Mr. Stéphane Mauger, Biologie Evolutive et Diversité Marine, Roscoff , France