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Standard Gene more Komplexe Gene more
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Gen Fragmente = GeneStrands

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Weitere wichtige Seiten

 

 

Gensynthese MSDSs

Häufige Fragen (FAQs)

GENEius

Plasmid/Vektor-Vorbereitung und Versand

 

Publikationen

 

Ausgewählte Publikationen zu den Themen Gensynthese, Molekularbiologie & Angewandte Genetik

2025

Gene synthesis: Giannone C., Mess X., He R. et al., How J-chain ensures the assembly of immunoglobulin IgM pentamers, The EMBO Journal

GeneStrands:  Poosakkannu A, Xu Y, Suominen KM, Meierhofer MB, Sørensen IH, Madsen JJ, Plaquin B, Guillemain M, Joyeux E, Keišs O, Lilley TM, Lehikoinen A, Pulliainen AT. 2025. Pathogenic bacterial taxa constitute a substantial portion of fecal microbiota in common migratory bats and birds in Europe. Microbiol Spectr

Gene synthesis: Esiobu N., Holmes D. et al. Synthetic Biology Construct of Ebola Virus in Bacteria Surrogate Is Stable and Safe for Rapid Detection Studies in a BSL-2 Laboratory Setting, Advances in Microbiology

Gene synthesis: Niemelä, L.R.K., Pásztor, A. & Frey, A.D. Generation of ribosomal protein S1 mutants for improving of expression of difficult to translate mRNAs. Appl Microbiol Biotechnol

Gene synthesis: Biermann, L.; Tadele, L.R.; Benatto Perino, E.H.; Nicholson, R.; Lilge, L.; Hausmann, R. Recombinant Production of Bovine αS1-Casein in Genome-Reduced Bacillus subtilis Strain IIG-Bs-20-5-1. Microorganisms

Gene synthesis: Guzman, J., Hart, M., Weigelt, K. et al. The MicroRNA miR-454 and the mediator complex component MED12 are regulators of the androgen receptor pathway in prostate cancer. Sci Rep

Gene synthesis: Schneider-Poetsch, T., Dang, Y., Iwasaki, W. et al. Girolline is a sequence context-selective modulator of eIF5A activity. Nat Commun

 

2024

Gene synthesis: Klingler F., Schlossbauer P., Naumann L., Handrick R., Hesse F., Neusüß C., Otte K., Developing microRNAs as engineering tools to modulate monoclonal antibody galactosylation, Biotechnology and Bioengineering

Gene synthesis: Dulyayangkul P. et al., Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics, PLOS Pathogens

Gene synthesis: Shintomi K et al., Recombinant cyclin B-Cdk1-Suc1 capable of multi-site mitotic phosphorylation in vitro, PLOS ONE

Gene synthesis: Capin et al, An engineered baculoviral protein and DNA co-delivery system for CRISPR-based mammalian genome editing, Nucleic Acids Research

Gene synthesis: Grafakou A., et al, Discovery of antiphage systems in the lactococcal plasmidome, Nucleic Acids Research

Gene synthesis: Dvořák, P., Burýšková, B., Popelářová, B. et al. Synthetically-primed adaptation of Pseudomonas putida to a non-native substrate D-xylose. Nat Commun

 

2023

Gene synthesis: Aguiar, T.Q., Oliveira, C., Domingues, L. (2023). Megaprimer-Based PCR to Synthesize Fusion Genes for Cloning. In: Domingues, L. (eds) PCR. Methods in Molecular Biology

Gene synthesis: Deletti, G., Green, S.D., Weber, C. et al. Unveiling an indole alkaloid diketopiperazine biosynthetic pathway that features a unique stereoisomerase and multifunctional methyltransferase. Nat Commun

Gene synthesis: Wu D., Gucwa M., Czub M., Cooper D., Shabalin I., Fritzen R., Arya S., Schwarz-Linek U., Blindauer C., Minor W., Stewart A.. Structural and biochemical characterisation of Co2+-binding sites on serum albumins and their interplay with fatty acids. Chemical Science

Gene synthesis: Tashiro, K., Segawa, T., Futami, T. et al. Establishment and characterization of a novel kidney cell line derived from the common bottlenose dolphin. In Vitro Cell.Dev.Biol.-Animal

Gene synthesis: Ishida Y, Koretsune T, Ishiuchi E, Teshima M and Ito M (2023) A magnesium transporter is involved in the cesium ion resistance of the high-concentration cesium ion-resistant bacterium Microbacterium sp. TS-1. Front. Microbiol.

Gene synthesis: Mamat U., Hein M., Grella D., Taylor C., Scholzen T., Alio I., Streit W., Huedo P., Coves X., Conchillo-Sole O., Gomez C., Gibert I., Yero D., Schaible U.. Improved mini-Tn7 Delivery Plasmids for Fluorescent Labeling of Stenotrophomonas maltophilia. Applied and Environmental Microbiology

Gene synthesis: Sauge-Merle, S.; Recuerda, M.; Beccia, M.R.; Lemaire, D.; Cherif, R.; Bremond, N.; Merola, F.; Bousmah, Y.; Berthomieu, C. Development of an Efficient FRET-Based Ratiometric Uranium Biosensor. Biosensors

Gene synthesis: Chronopoulou S., Tsochantaridis I., Tokamani M., Kokkinopliti K., Tsomakidis P., Giannakakis A., Galanis A., Pappa A., Sandaltzopoulos R. Expression and purification of human interferon alpha 2a (IFNα2a) in the methylotrophic yeast Pichia pastoris,
Protein Expression and Purification

 

2022

Gene synthesis: Di Nitto C, Neri D, Weiss T, Weller M, De Luca R. Design and Characterization of Novel Antibody-Cytokine Fusion Proteins Based on Interleukin-21. Antibodies. 2022

GeneStrands: Forrest, D., Warman, E.A., Erkelens, A.M. et al. Xenogeneic silencing strategies in bacteria are dictated by RNA polymerase promiscuity. Nat Commun

Gene synthesis: Liu et al. Bivalent single domain antibody constructs for effective neutralization of Venezuelan equine encephalitis. Scientific reports

Gene synthesis: Reimer et al. Engineering the amoeba Dictyostelium discoideum for biosynthesis of a cannabinoid precursor and other polyketides. Nature Biotechnology

 

SARS-CoV-2 research: Signorini et al. Longitudinal, virological, and serological assessment of hospitalized COVID-19 patients

SARS-CoV-2 research: Monteiro et al. Recovery of SARS-CoV-2 from large volumes of raw wastewater is enhanced with the inuvai R180 system. Journal of Environmental Management

SARS-CoV-2 research: Herrlein et al. Comparative Investigation of Methods for Analysis of SARS-CoV-2-Spike-Specific Antisera. Viruses

 

2021

SARS-CoV-2 research: Anna et. al., High seroprevalence but short‐lived immune response to SARS‐CoV‐2 infection in Paris

SARS-CoV-2 research: Rajasekharan et. al., Inhibitors of Protein Glycosylation Are Active against the Coronavirus Severe Acute Respiratory Syndrome Coronavirus SARS-CoV-2

SARS-CoV-2 research: Bechtold et. al., Rapid Identification of SARS-CoV-2 Variants of Concern Using a Portable peakPCR Platform

 

Gene synthesis: Marusic, et al., The expression in plants of an engineered VP2 protein of Infectious Bursal Disease Virus induces formation of structurally heterogeneous particles that protect from a very virulent viral strain

Gene synthesis: Shams, et al., Evaluation of the Binding Kinetics of RHEB with mTORC1 by In-cell and In vitro Assays

Gene synthesis: Unno, et al., Heterologous expression of cryptic biosynthetic gene cluster from Streptomyces prunicolor yields novel bicyclic peptide prunipeptin

Gene synthesis: Nakazato, et al., Targeted base editing in the plastid genome of Arabidopsis thaliana

Gene synthesis: Marine, et al., Towards unravelling the Rosette agent enigma: Spread and emergence of the co-invasive host-pathogen complex, Pseudorasbora parva-Sphaerothecum destruens

Gene synthesis: Johari, et al., Design of synthetic promoters for controlled expression of therapeutic genes in retinal pigment epithelial cells

Gene synthesis: Wang, et al., A glycoengineered antigen exploiting a conserved protein O-glycosylation pathway in the Burkholderia genus for detection of glanders infections

2020

Gene synthesis: Wong T.S., Tee K.L. (2020) Gene Cloning. In: A Practical Guide to Protein Engineering. Learning Materials in Biosciences. Springer, Cham

SARS-CoV-2 research: Ruiz-Arrondo., et al., Detection of SARS‐CoV‐2 in pets living with COVID‐19 owners diagnosed during the COVID‐19 lockdown in Spain: A case of an asymptomatic cat with SARS‐CoV‐2 in Europe

Gene synthesis: Ferrari et al., The allergen Mus m 1.0102: Cysteine residues and molecular allergology, Molecular Immunology

Gene synthesis: Fernandes et al., The dimerisable Cre recombinase allows conditional genome editing in the mosquito stages of Plasmodium berghei

2019

Gene synthesis: Abu-Halima M., et al., Differential expression of miR-23a/b-3p and its target genes in male patients with subfertility

Gene synthesis: Johari Y. B., et al., CHO genome mining for synthetic promotor design, 

Gene synthesis: Sota M., et al., Efficient transposition of Tn4556 by alterations in inverted repeats using a delivery vector carrying a counter-selectable marker for Streptomyces

Gene synthesis: Jimmy S., et al., Discovery of small alarmone synthetases and their inhibitors as toxin-antitoxin loci

Gene synthesis: Liu J., et al., Polychromatic solar energy conversion in pigment-protein chimeras that unite the two kingdoms of (bacterio)chlorophyll-based photosynthesis

Gene synthesis: Tebo AG., et al., A plit fluorescent reporter with rapid and reversible complementation

2018

Gene synthesis: Jaubert, C. et al., RNA synthesis is modulated by G-quadruplex formation in Hepatitis C virus negative RNA strand

Gene synthesis: Fusco, F. A. et al., Biochemical charaterization of a thermostable endomannanase / endoglucanase from Dictyoglomus turgidum

Gene synthesis: Bernardini A. et al., The phosphorylatable Ser320 of NF-YA is involved in DNA binding of the NF-Y trimer

Gene synthesis: Amiri, M. M. et al., Hersintuzumab: A novel humanized anti-HER2 monoclonal antibody induces potent tumor growth inhibition

Gene synthesis: Fathi, S. et al., Design and construction of a new recombinant fusion protein (2b2t+EPC1) and its assessment for serodiagnosis of cystic echinococcosis

Gene synthesis: Brenner, N. et al., Validation of Multiplex Serology detecting human herpesviruses 1-5

Gene synthesis: Nolvak, H. et al., Reduction of antibiotic resistome and integron-integrase genes in laboratory scale photobioreactors treating municipal wastewater

Gene synthesis: Chow J., et al., The Thaumarchaeon N. gargensis carries functional bioABD genes and has a promiscuous E. coli deltabioH-complementing esterase EstN1

2017

Gene synthesis: Le, T, M. et al., Vectors for Expression of Signal Peptide-Dependent Proteins in Baculovirus/Insect Cell Systems and Their Application to Expression and Purification of the High-Affinity Immunoglobulin Gamma Fc Receptor I in Complex with Its Gamma Chain.

Gene synthesis: Mekonnen S. et al., O-5S quantitative real-time PCR: a new diagnostic tool for laboratory confirmation of human onchocerciasis

Gene synthesis: Wingen, M. et al., Novel Thermostable Flavin‐binding Fluorescent Proteins from Thermophilic Organisms

2016

Gene synthesis: Nolvak H., et al., Inorganic and organic fertilizers impact the abundance and proportion of antibiotic resistance and integron-integrase genes in agricultural grassland soil

Gene synthesis: Whitten MM., et al., Symbiont-mediated RNA interference in insects

Gene synthesis: Ohno M., et al., Acidic mammalian chitinase is a proteases-resistant glycosidase in mouse digestive system

Gene synthesis: Hoshiba T., Decellularized matrices as in vitro models of extracellular matrix in tumor tissues at different malignant levels: Mechanism of 5-fluorouracil resistance in colorectal tumor cells

Gene synthesis: Turner K.B., et al., Next-Generation Sequencing of a Single Domain Antibody Repertoire Reveals Quality of Phage Display Selected Candidates

Gene synthesis: Sudo Y., et al., Functional and Photochemical Characterization of a Light‐Driven Proton Pump from the Gammaproteobacterium Pantoea vagans

Gene synthesis: Scorsone E., et al., Major Urinary Proteins on Nanodiamond-Based Resonators Toward Artificial Olfaction

2015

Gene synthesis: Brieke, C. et al., Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics. Organic & biomolecular chemistry

Gene synthesis: Takeishi, R. et al., Epimerization at C-3′′ in Butirosin Biosynthesis by an NAD+-Dependent Dehydrogenase BtrE and an NADPH-Dependent Reductase BtrF. ChemBioChem

 

2014

Gene synthesis: Buettner, K. et al., Protein surface charge of trypsinogen changes its activation pattern. BMC biotechnology 14(1)

Gene synthesis: Chiwata, R. et al., None of the Rotor Residues of F 1-ATPase Are Essential for Torque Generation. Biophysical journal 106(10)

Gene synthesis: Holmberg, M. et al., A versatile bacterial expression vector designed for single-step cloning of multiple DNA fragments using homologous recombination. Protein expression and purification 98

Gene synthesis: Dietz O. et al., Characterization of the small exported Plasmodium falciparum membrane protein SEMP1. PLOS ONE 9(7): e103272

Gene synthesis: Canali E. et al., A high-performance thioredoxin-based scaffold for peptide immunogen construction: proof-of-concept testing with a human papillomavirus epitope. Nature Scientific Reports 4(4729)

 

2013

Gene synthesis: Mueller W. et al., Hierarchical organization of multi-site phosphorylation at the CXCR4 C Terminus, PLOS ONE 8(5): e64975

Gene synthesis:
Van Noort, V., Bradatsch, B., Arumugam, M., Amlacher, S et al.,  Consistent mutational paths predict eukaryotic thermostability. BMC Evolutionary Biology, 13(1), 7

 

2012

Gene synthesis: Carciofi M. et al. Concerted suppression of all starch branching enzyme genes in barely produces amylose-only starch granules. BMC Plant Biology 2012, 12:223

Gene synthesis: Lejonklou M. et al. Accelerated Proliferation and Differential Global Gene Expression in Pancreatic Islets of Five-Week-Old Heterozygous Men1 Mice: Men1 Is a Haploinsufficient Suppressor. Endocrinology April 2012 (Genes purchase/synthesis: kinase complex-associated protein (Ikbkap)

Cloning: Ullrich T. et al. Competitive Reporter Monitored Amplification (CMA) - Quantification of Molecular Targets by Real Time Monitoring of Competitive Reporter Hybridization. PLoS ONE 7(4): e35438. (IPC gene for HIV- 1 and HIV- 2 respectively cloned into the pCR 2.1 TOPO® vector)

Gene synthesis: Ritari J. et al. Detection of Human Papillomaviruses by Polymerase Chain Reaction and Ligation Reaction on Universal Microarray. PLoS ONE 7(3): e34211. (HPV sequences were synthesised and cloned into plasmid vector)

Site-directed mutatgenesis: Esposito F. et al. Down-Regulation of the miR-25 and miR-30d Contributes to the Development of Anaplastic Thyroid Carcinoma Targeting the Polycomb Protein EZH2. Journal of Clincial Endocrinology & Metabolism May 1, 2012 vol. 97 no. 5 E710-E718


2011

Gene synthesis: Weber E. et al. Assembly of Designer TAL Effectors by Golden Gate Cloning. PLoS ONE 6(5): e19722

Gene synthesis: Gays F. et al. Comprehensive Analysis of Transcript Start Sites in Ly49 Genes Reveals an Unexpected Relationship with Gene Function and a Lack Of Upstream Promoters. PLoS ONE 6(3): e18475.

 

 

 

 

 

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