Helping to improve patients outcome by:

• Comprehensive genomic cancer profiling (CGP) of 591 cancer genes
• Exome sequencing (WES)
• Whole genome sequencing (WGS)
• Pharmacogenomics (PGx)
• Hotspot actionable variant genotyping (Oncotarget)
• Fusion transcripts and gene expression profiling
• Structural variant detection (SVs, CNVs)
• Liquid biopsy solutions
• Minimal residual disease (MRD)
• Companion diagnostics
• Kit development and logistics

All services are available GCP compliant:

• Inclusion criteria testing
• Pharmocogenetic services (PGx)
• Safety testing, e.g.: vector shedding, RCR, RCV, VCN, residual host cell DNA
• Adventitious virus testing
• Expression profiling and biomarker testing
• Logistic and central laboratory services
• Cell line authentication and mycoplasma check service
• Sanger, NGS, dPCR and qPCR services
• Quality control (QC) services

Determine the mutational status:

• Tumour mutational burden analyses (TMB)
• Micro satellite instability testing (MSI)
• Homologous recombination deficiency scoring (HRD)
• Copy number aberration burden (CNA burden)
• Neoantigen detection
• Utilising comprehensive genomic profiling, exome, genome and transcriptome sequencing
• Minimal residual disease (MRD) testing
• Liquid biopsy solutions

• Residual host cell DNA testing
• Adventitious virus testing
• Vector shedding, RCR, RCV, VCN testing
• Cell line authentication and mycoplasma check service
• Testing modified genomes (e.g.: CAR-T cells)
• GLP accredited solutions, GCP compliant services
• Toxicology screening solutions

Benefit from our unique comprehensive toolbox to detect:

• Chromosomal rearrangements
• Fusion genes
• Copy number variations (CNV)
• Telomeric aberrations
• Comparative genomic hybridization (CGH) Array
• Loss of heterozygosity (LOH)
• Insertions and Deletions

Profile you tumour sample for fusion transcripts, differential gene expression, splice variants and neoantigens with:

• Stranded library sequencing
• RNA Exome sequencing
• FFPE expression analysesUltra low amount RNA sequencing
• Whole transcriptome arrays and biobank screenings
• Single gene and marker expression testing
• miRNA profiling

Understanding the cancer patient analysing cfDNA and CTC DNA from plasma, liquor and urine:

• Hotspot actionable variant genotyping (Oncotarget)
• Custom qPCR and dPCR assays
• Low pass whole genome sequencing
• Whole exome sequencing
• Comprehensive genomic cancer profiling (CGP) of 591 cancer genes
• Custom NGS panels
• Targeted bisulfite sequencing
• ThermoFisher and Illumina oncology arrays

Decode the epigenome in various ways:

• Genome wide methylation array (EPIC)
• Whole genome bisulfite sequencing (WGBS)
• Reduced representation bisulfite sequencing (RRBS)
• Target bisulfite sequencing from liquid biopsies
• Custom targeted assay development

Complete Eurofins group oncology service world:

• Pathology, histology, immunohistochemistry
• Cell line and compound testing
• CDMO service
• Biopharma product testing
• Central lab services
• Medical diagnostic laboratory service