Whole genome sequencing (WGS) delivers exact DNA sequence data for the entire genome of an organism. It is based on next-generation sequencing (NGS), also known as high-throughput sequencing, which is a massively parallel DNA sequencing technology that allows for the analysis of samples and systems at a level that was never possible before. NGS machines can sequence large samples more cost-effectively than traditional methods, and in the process also generate more detailed genomic information.

WGS cannot only be used in the case of microbial contamination issues. It can also be a useful tool for a full characterisation of valuable production strains. The knowledge of the whole genome sequence leads to a unique definition of the production strain. This can be very helpful in case of e.g. patent infringement issues.

Complex bacterial / fungal mixed populations can also be analysed by WGS. Our “Microbiota Screening Services” enable an insight into the microflora of food / environmental samples as well as fermentation processes by the use of so-called barcoding regions in the microbial DNA, thus identifying the genus or species. Our “Metagenomics Service” looks at the total DNA of a complex sample containing mixed populations and allows for an identification of strains and subspecies. Both approaches include and identify even non-cultivatable microorganisms.