Oncology solutions for all sample types. Experts in FFPE and Liquid Biopsies

Your genomics partner in oncology

Answer any DNA and RNA related question

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Research

Precision oncology

Clinical trials

Safety testing

Our GENOMICS Solutions for ONCOLOGY

We provide all the solutions you will need

Biomarkers

Precision oncology

Helping to improve patients outcome by:

Comprehensive genomic cancer profiling (CGP) of 591 cancer genes
Exome sequencing (WES)
Whole genome sequencing (WGS)
Pharmacogenomics (PGx)
Hotspot actionable variant genotyping (Oncotarget)
Fusion transcripts and gene expression profiling
Structural variant detection (SVs, CNVs)
Liquid biopsy solutions
Minimal residual disease (MRD)
Companion diagnostics
Kit development and logistics

Clinical trials

All services are available GCP compliant:

Inclusion criteria testing
Pharmocogenetic services (PGx)
Safety testing, e.g.: vector shedding, RCR, RCV, VCN, residual host cell DNA
Adventitious virus testing
Expression profiling and biomarker testing
Logistic and central laboratory services
Cell line authentication and mycoplasma check service
Sanger, NGS, dPCR and qPCR services
Quality control (QC) services

Immuno-Oncology

Determine the mutational status:

Tumour mutational burden analyses (TMB)
Micro satellite instability testing (MSI)
Homologous recombination deficiency scoring (HRD)
Copy number aberration burden (CNA burden)
Neoantigen detection
Utilising comprehensive genomic profiling, exome, genome and transcriptome sequencing
Minimal residual disease (MRD) testing
Liquid biopsy solutions

Safety testing

Residual host cell DNA testing
Adventitious virus testing
Vector shedding, RCR, RCV, VCN testing
Cell line authentication and mycoplasma check service
Testing modified genomes (e.g.: CAR-T cells)
GLP accredited solutions, GCP compliant services
Toxicology screening solutions

Structural variants

Benefit from our unique comprehensive toolbox to detect:

Chromosomal rearrangements
Fusion genes
Copy number variations (CNV)
Telomeric aberrations
Comparative genomic hybridization (CGH) Array
Loss of heterozygosity (LOH)
Insertions and Deletions

Transcript and RNA

Profile you tumour sample for fusion transcripts, differential gene expression, splice variants and neoantigens with:

Stranded library sequencing
RNA Exome sequencing
FFPE expression analysesUltra low amount RNA sequencing
Whole transcriptome arrays and biobank screenings
Single gene and marker expression testing
miRNA profiling

Liquid biopsy

Understanding the cancer patient analysing cfDNA and CTC DNA from plasma, liquor and urine:

Hotspot actionable variant genotyping (Oncotarget)
Custom qPCR and dPCR assays
Low pass whole genome sequencing
Whole exome sequencing
Comprehensive genomic cancer profiling (CGP) of 591 cancer genes
Custom NGS panels
Targeted bisulfite sequencing
ThermoFisher and Illumina oncology arrays

Epigenetics

Decode the epigenome in various ways:

Genome wide methylation array (EPIC)
Whole genome bisulfite sequencing (WGBS)
Reduced representation bisulfite sequencing (RRBS)
Target bisulfite sequencing from liquid biopsies
Custom targeted assay development

Beyond genomics

Complete Eurofins group oncology service world:

Pathology, histology, immunohistochemistry
Cell line and compound testing
CDMO service
Biopharma product testing
Central lab services
Medical diagnostic laboratory service

Full scalability
100 %
From one to thousands of samples.
Don’t be afraid to think big!

tackle your challenges

Our technologies

We provide everything you need:

Next-generation sequencing (Illumina and Oxford Nanopore Technologies platforms)
Microarrays (all Illumina and Thermo Fisher platforms)
qPCR / dPCR
Sanger sequencing
Oligo synthesis
Gene synthesis
DNA / RNA extractions
Assay design & validation
Bioinformatics
Bio-banking
Sampling kits supply and logistics network

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Express solutions

Make full use of our high capacities, high reliability, and fastest turnaround time

1 business day qPCR/dPCR biomarker testing
5 business days microarray service
9 business days exome
9 business days comprehensive genomic profiling
10 business days whole human genome
Fastest logistics solutions
Shortest response time

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Quality is our second name

Work with a fully certified partner

ISO 17025

Guaranteed confidentiality and integrity of testing data.

Testing results are recognised by authorities and customs, etc. for the release of pharmaceuticals and food and feed, in the case of legal implications

ISO 13485

Full documentation and traceability of production processes.

Compliance with regulatory requirements in regard to EU, US and other national directives about medical devices, in vitro Diagnostics or medicinal products.

Quality management system is in line with the FDA QSR standards.

ISO 9001

Short production times due to highly optimised and structured processes.

Well trained, competent and highly qualified personnel.

Fully documented processes.

Effective complaint and CAPA management.

GCLP

Guaranteed confidentiality and integrity of clinical trial data.

Full protection of patient rights, safety and well-being.

Full compliance with GCLP regulatory requirements.

Acceptance of clinical study data by regulatory authorities in EU, US and worldwide.

GLP

Full traceability of GLP study data.

GLP compliant archiving of study data and records.

Full compliance with GLP regulatory requirements (OECD, EMA, US-FDA, US-EPA).

Acceptance of non-clinical safety study data by regulatory authorities in EU, US and worldwide.

We are the one provider that covers all aspects of your project

Benefit from our large network of labs and technologies

Eurofins Genomics as part of Eurofins Scientific is a market leader in services for genomics, discovery pharmacology and clinical studies. With our globally unrivalled lab network, we support standard and challenging research projects, as well as complex strategies for large interdisciplinary companies.

We support from research to application:

Pharma | Diagnostics | Biotechnology

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You are in good company – we are approved by our peers

Eurofins Genomics is a trusted brand around the globe

We cooperate with 16 of the TOP 20 Big Pharma companies

We cooperate with renowned organisations ranging from small-, medium- and large-scale enterprises to academic institutions. We provide leading expertise and sequencing capabilities that are needed to address some of today’s most important scientific and technical challenges.

We are scientific partners with

We are cooperation partners with

LEARN MORE

Interesting articles and webinars

Application of genomics solutions in oncology

Digital PCR

dPCR is used in oncology and enables precise and sensitive cancer diagnostics. Find out how cfDNA in bodily fluids is used for cancer diagnostics by dPCR.

NGS AS CLINICAL DIAGNOSTICS TOOL IN ONCOLOGY

Genome analysis of cancers is used to choose the most effective cancer therapies, called personalised medicine. Learn how NGS is used in diagnostics for oncology.

ONCOMPASS – TRUSTED PARTNER FOR PERSONALISED CANCER THERAPY

Personalised cancer therapy is complicated and Oncompass provides navigation to decide for the best-suited therapy.

Cancer Ecology

What do invasive species and metastasis have in common? What is the effect of selective pressure on cancer cells and how does this impact cancer therapy?

Speak to our expert

Festival of Genomics 2021 Webinar

Better than exomes

Better than panels. What are the relative genomic aberrations in tumours? Analyse virtually all cancer-associated genes with one solution: Comprehensive genomic cancer profiling.

Watch the full webinar

Your dedicated Oncology Experts

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